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ProductsBack/NOD1/2 antagonist-1

NOD1/2 antagonist-1

Research Use Only

HY-146034

Molecular Weight663.03

Product group Chemicals

Overview

Supplier
MedChem Express
Product Name
NOD1/2 antagonist-1
Delivery Days Customer
10
Certification
Research Use Only
Molecular Formula
C32H28ClF5N4O4
Molecular Weight
663.03
Scientific Description
NOD1/2 antagonist-1 (compound 36b) is a potent NOD1/2 (nucleotide-binding oligomerization domain-like receptor 1/2) dual antagonist, with IC50 values of 1.13 (NOD1) and 0.77 microM (NOD2), respectively. NOD1/2 antagonist-1 has a acceptable T1/2 (67.6 min). NOD1/2 antagonist-1 (compound 36b) can improve the antitumor efficacy of Paclitaxel (PTX).
SMILES
O=C(C1=C(C=C2C(N(C=NC2=C1)CC(N3CCCC(F)(C3)F)=O)=O)C4=CC(Cl)=CC=C4)NCCCOC5=CC=C(C=C5)C(F)(F)F
Storage Instruction
See Manual
UNSPSC
12352200