Bio-Connect

NOD2 Polyclonal Antibody

Research Use Only
RD76743A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNOD2
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    NOD2 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.8 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID64127
  • Target name
    NOD2
  • Target description
    nucleotide binding oligomerization domain containing 2
  • Target synonyms
    ACUG; BLAU; BLAUS; CARD15; caspase recruitment domain family, member 15; caspase recruitment domain protein 15; caspase recruitment domain-containing protein 15; CD; CLR16.3; IBD1; inflammatory bowel disease protein 1; NLR family, CARD domain containing 2; NLRC2; NOD2B; NOD-like receptor C2; nucleotide-binding oligomerization domain 2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2; nucleotide-binding oligomerization domain-containing protein 2; PSORAS1; YAOS
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203