Nodakenetin

Selleck Chemicals

Nodakenetin

9

Research Use Only

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Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits alpha-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and beta-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity.

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