Nonapeptide-1

MedChem Express

Nonapeptide-1 [158563-45-2]

10

Research Use Only

99.04

Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R ( K i : 40 nM). Nonapeptide-1 is a competitive alpha-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by alpha-MSH in melanocytes ( IC 50 : 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer [1] [2] [3] .

-20°C,-80°C

12352202