NOS2 Antibody, FITC conjugated

Cusabio

NOS2 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

NOS2

nitric oxide synthase 2

hepatocyte NOS; HEP-NOS; inducible NO synthase; inducible NOS; INOS; nitric oxide synthase 2, inducible; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; NOS; NOS, type II; NOS2A; peptidyl-cysteine S-nitrosylase NOS2

Rabbit

IgG

Nitric oxide synthase, inducible

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on \Cys-247\ implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109).

Human

-20°C or -80°C

12352203