Various whole cell extracts (30 microg) were separated by 5% SDS-PAGE, and the membrane was blotted with NOTCH1 antibody (GTX135786) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Various whole cell extracts (30 microg) were separated by 5% SDS-PAGE, and the membrane was blotted with NOTCH1 antibody (GTX135786) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
NOTCH1 antibody
GTX135786
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameNOTCH1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.95 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203