Novobiocin Sodium [1476-53-5]
N5986
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameNovobiocin Sodium [1476-53-5]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- Format50mg/ml in water
- Scientific DescriptionAminocoumarin; bacterial DNA gyrase inhibitor.
- Storage InstructionAmbient
- UNSPSC12352200
References
- Gunaherath GM, Marron MT, Wijeratne EM, et al. Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors. Bioorg Med Chem. 2013 Sep 1;21(17):5118-29. PMID: 23859777. Wu D, Zhang R, Zhao R, et al. A novel function of novobiocin: disrupting the interaction of HIF 1alfa and p300/CBP through direct binding to the HIF1alfa C-terminal activation domain. PLoS One. 2013 May 6;8(5):e62014. PMID: 23671581. Walsh TJ, Standiford HC, Reboli AC, et al. Randomized Double-Blinded Trial of Rifampin with Either Novobiocin or Trimethoprim-Sulfamethoxazole against Methicillin-Resistant Staphylococcus aureus Colonization: Prevention of Antimicrobial Resistance and Effect of Host Factors on Outcome. Antimicrobial agents and chemotherapy 1993 Jun;37(6):1334–42. PMID: 8328783. Maxwell A. The interaction between coumarin drugs and DNA gyrase. Mol Microbiol 1993;9(4):681–6. PMID: 8231802.