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NOX4 / NADPH Oxidase 4 (NOX4/1245), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401245
Biotium
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetNOX4
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Overview

  • Supplier
    Biotium
  • Product Name
    NOX4 / NADPH Oxidase 4 (NOX4/1245), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    NOX4/1245
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID50507
  • Target name
    NOX4
  • Target description
    NADPH oxidase 4
  • Target synonyms
    kidney oxidase-1; kidney superoxide-producing NADPH oxidase; KOX; KOX-1; NADPH oxidase 4; renal NAD(P)H-oxidase; RENOX
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDQ9NPH5
  • Protein Name
    NADPH oxidase 4
  • Scientific Description
    The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203