Bio-Connect

NPD-001 [469863-16-9]

HY-136637
MedChem Express
CAS Number469863-16-9
Product group Chemicals
Estimated Purity98.11
Molecular Weight584.72
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NPD-001 [469863-16-9]
  • Delivery Days Customer
    10
  • CAS Number
    469863-16-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.11
  • Molecular Formula
    C33H40N6O4
  • Molecular Weight
    584.72
  • Scientific Description
    NPD-001 is a potent Trypanosoma brucei phosphodiesterases TbrPDEB1 and TbrPDEB2 inhibitor, with IC50 values of 4 and 3 nM, respectively. NPD-001 also inhibits human PDEs (phosphodiesterases). NPD-001 shows good anti trypanosomal activity, with an IC50 of 80 nM[1].
  • SMILES
    O=C1N(C2CCCCCC2)N=C(C3=CC=C(OC)C(OCCCCOC4=CC=C(C5=NN=NN5)C=C4)=C3)[C@@]6([H])CC=CC[C@@]16[H]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200