NPD-1335 [2376326-31-5]
T12250
Overview
- SupplierTargetMol Chemicals
- Product NameNPD-1335 [2376326-31-5]
- Delivery Days Customer72
- CAS Number2376326-31-5
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameNPD-1335
- Molecular FormulaC28H29N3O3
- Molecular Weight455.55
- Scientific DescriptionNPD1335, a potent inhibitor of Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1), exhibits submicromolar activity against T. brucei parasites and an improved cytotoxicity profile. By elevating intracellular cAMP levels, NPD1335 disrupts the cell cycle, leading to cell death [1].
- Shelf life instruction3 years
- SMILES[H][C@]12CC=CC[C@@]1([H])C(=NN(C(C)C)C2=O)c1ccc(OC)c(c1)C#CC(=O)NCc1ccccc1
- Storage Instruction-20°C
- UNSPSC12352200
