Bio-Connect

NPHS2 Polyclonal Antibody

RD79189A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNPHS2
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    NPHS2 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.4 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7827
  • Target name
    NPHS2
  • Target description
    NPHS2 stomatin family member, podocin
  • Target synonyms
    nephrosis 2, idiopathic, steroid-resistant (podocin); NPHS2, podocin; PDCN; podocin; SRN1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203