NR2F1 agonist 1 [374101-64-1]

MedChem Express

NR2F1 agonist 1 [374101-64-1]

10

374101-64-1

Research Use Only

99.06

C28H30N4OS

470.63

NR2F1 agonist 1, a nuclear receptor NR2F1 agonist, specifically activates dormancy programs in malignant cells. NR2F1 agonist 1 up-regulates NR2F1 and downstream target genes that regulate dormancy. NR2F1 agonist 1 induces neural crest-like and growth suppression in head and neck squamous cell carcinoma (HNSCC) via NR2F1 activation. NR2F1 agonist 1 inhibits tumor growth in a mouse primary tumor model[1].

O=C1C2=C(N3C(SCC)=NN=C3N1CCC4=CC=CC=C4)C5=C(CC26CCCCC6)C=CC=C5

2°C to 8°C

12352200