Immunohistochemical analysis of paraffin-embedded human brain tissue using GR (Ab-226) antibody.
NR3C1 (Ab-226) Antibody
CSB-PA589113
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNR3C1
Overview
- SupplierCusabio
- Product NameNR3C1 (Ab-226) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2908
- Target nameNR3C1
- Target descriptionnuclear receptor subfamily 3 group C member 1
- Target synonymsGCCR; GCR; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; GR; GRL; nuclear receptor subfamily 3 group C member 1 variant hGR-B(54); nuclear receptor subfamily 3 group C member 1 variant hGR-B(77); nuclear receptor subfamily 3 group C member 1 variant hGR-B(93); nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
- HostRabbit
- IsotypeIgG
- Protein IDP04150
- Protein NameGlucocorticoid receptor
- Scientific DescriptionReceptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. Kyung Jin Kwak, J. Exp. Bot., Nov 2005; 56: 3007 - 3016. Maite de Llanos, Hum. Reprod., Jan 2005; 20: 216 - 220. M. Lynch, Mol. Hum. Reprod., Jul 2005; 11: 507 - 512. Valeriya P. Makarenkova, J. Immunol., Feb 2006; 176: 2085 - 2094.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203