NRCAM antibody [7D8C5]

GeneTex

NRCAM antibody [7D8C5]

9

WB: 1/500 - 1/2000. ICC/IF: 1/50. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

7D8C5

1 mg/ml

Unconjugated

NRCAM

neuronal cell adhesion molecule

neuronal cell adhesion molecule; neuronal surface protein Bravo; NgCAM-related cell adhesion molecule

Mouse

IgG1

Neuronal cell adhesion molecule

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203