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NRX-103095 [2763260-38-2]

NRX-103095 [2763260-38-2]

T63730
TargetMol Chemicals
Estimated Purity99.60%
DownloadMSDS
Product group Chemicals
Molecular Weight530.35
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    NRX-103095 [2763260-38-2]
  • Delivery Days Customer
    9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    NRX-103095
  • Estimated Purity
    99.60%
  • Molecular Formula
    C22H16Cl2F3N3O3S
  • Molecular Weight
    530.35
  • Scientific Description
    NRX-103095 is a potent enhancer of the interaction of beta-catenin with the homologous E3 ligase SCFbeta-TrCP and enhances the affinity of pSer33/Ser37 beta-catenin for beta-TrCP with an EC50 of 163 nM.
  • Shelf life instruction
    3 years
  • SMILES
    S(C1=C(C(NC2=CC(C(N(C)C)=O)=CC=C2)=O)C(=O)NC(C(F)(F)F)=C1)C3=C(Cl)C=CC=C3Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Simonetta KR et al., 2019 Mar 29, Nat Commun
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