NS-11394 [951650-22-9]
N7200
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameNS-11394 [951650-22-9]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatDMSO:43mg/ml
- Scientific DescriptionGABA-A alfa5/3/2 positive modulator.; NS11394; UNII-1PTH9FK74J; NS 11394; 1PTH9FK74J
- Storage Instruction-20°C
- UNSPSC12352200
References
- Hofmann M, Kordás KS, Gravius A, et al. Assessment of the effects of NS11394 and L-838417, alfa2/3 subunit-selective GABA(A) [corrected] receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function. Behav Pharmacol. 2012 Dec;23(8):790-801. Erratum in: Behav Pharmacol. 2013 Apr;24(2):153. PMID: 23075708. Hansen RR, Erichsen HK, Brown DT, et al. Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats. Neuropharmacology. 2012 Dec;63(8):1360-7. PMID: 22985969. Mirza NR, Larsen JS, Mathiasen C, et al. NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile], a unique subtype-selective GABAA receptor positive allosteric modulator: in vitro actions, pharmacokinetic properties and in vivo anxiolytic efficacy. J Pharmacol Exp Ther. 2008 Dec;327(3):954-68. PMID: 18791063.