NT376 [2820208-97-5]

TargetMol Chemicals

NT376 [2820208-97-5]

9

Research Use Only

C21H20F4N4O2

436.4

NT376 is a potent and selective inhibitor of class IIa Histone deacetylases (HDAC), exhibiting an IC50 value of 32 nM and demonstrating efficacy similar to NT160 (IC50 = 46 nM) in HT-29 cells. This compound is a promising candidate for research into various cancers and central nervous system (CNS) disorders, including Alzheimers and Huntingtons diseases.

C(F)(F)(F)C1=NC(=NO1)C2=CC(F)=C(C(N[C@@H](CN(CC3=CC=CC=C3)C)C)=O)C=C2

-20°C

12352200