NTRK1 Polyclonal Antibody

Reddot Biotech

NTRK1 Polyclonal Antibody

5

0.8 mg/ml

NTRK1

neurotrophic receptor tyrosine kinase 1

gp140trk; high affinity nerve growth factor receptor; MTC; neurotrophic tyrosine kinase, receptor, type 1; Oncogene TRK; p140-TrkA; TRK; TRK1; TRK1-transforming tyrosine kinase protein; TRKA; Trk-A; tropomyosin-related kinase A; tyrosine kinase receptor A

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

-20°C

12352203