NTU281

MedChem Express

NTU281

10

C25H31N2O6S

487.59

NTU281 is a potent transglutaminase-2 inhibitor. NTU281 can reduce the increases in serum creatinine and albuminuria in diabetic rats. NTU281 can also reduce glomerular collagen I accumulation, Hic-5 and alpha-SMA expression, and apoptosis . NTU281 can be used for researching glomerulosclerosis caused by diabetes [1] [2] .

O=C(N[C@H](C(N[C@@H](CCC(C[S+](C)C)=O)C(O)=O)=O)CC1=CC=CC=C1)OCC2=CC=CC=C2

12352200