NU6140

MedChem Express

NU6140 [444723-13-1]

10

444723-13-1

Research Use Only

99.07

C23H30N6O2

422.52

NU6140 is a selective CDK2-cyclin A inhibitor ( IC 50 , 0.41 microM), exhibits 10- to 36-fold selectivity over other CDKs [1] . NU6140 also potently inhibits Aurora A and Aurora B , with IC 50 s of 67 and 35 nM, respectively [2] . Enhances the apoptotic effect, with anti-cancer activity [1] [2] .

CCN(CC)C(C(C=C1)=CC=C1NC2=NC(OCC3CCCCC3)=C4C(N=CN4)=N2)=O

-20°C,2°C to 8°C

12352200