More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/NUAK1 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using NUAK1 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using NUAK1 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using NUAK1 Polyclonal Antibody at dilution 1:60

NUAK1 Polyclonal Antibody

E-AB-12986
Elabscience
Product group Antibodies
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Elabscience
  • Product Name
    NUAK1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.6mg/ml
  • Scientific Description
    NUAK family SNF1-like kinase 1also known asAMPK-related protein kinase 5(ARK5) is anenzymethat in humans is encoded by theNUAK1gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of Ser-464 of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.
  • UNSPSC
    12352203