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Nucleoredoxin antibody [N3C3]

GTX107039
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse
TargetNXN
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Overview

  • Supplier
    GeneTex
  • Product Name
    Nucleoredoxin antibody [N3C3]
  • Delivery Days Customer
    9
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.79 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID64359
  • Target name
    NXN
  • Target description
    nucleoredoxin
  • Target synonyms
    NRX; nucleoredoxin; nucleoredoxin 1; RRS2; TRG-4
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ6DKJ4
  • Protein Name
    Nucleoredoxin
  • Scientific Description
    Functions as a redox-dependent negative regulator of the Wnt signaling pathway. May function as a transcriptional regulator. May regulate phosphatase 2A.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Flightless-I is a potential biomarker for the early detection of alcoholic liver disease. Arellanes-Robledo J et al., 2021 Jan, Biochem Pharmacol
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  • Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease. Alarcon-Sanchez BR et al., 2020 Nov, Basic Clin Pharmacol Toxicol
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  • Ethanol targets nucleoredoxin/dishevelled interactions and stimulates phosphatidylinositol 4-phosphate production in vivo and in vitro. Arellanes-Robledo J et al., 2018 Oct, Biochem Pharmacol
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  • Fibrogenic actions of acetaldehyde are beta-catenin dependent but Wingless independent: a critical role of nucleoredoxin and reactive oxygen species in human hepatic stellate cells. Arellanes-Robledo J et al., 2013 Dec, Free Radic Biol Med
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