Western blot analysis of extracts of various cell lines using NUDT15 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using NUDT15 Polyclonal Antibody at dilution of 1:1000.
NUDT15 Polyclonal Antibody
E-AB-62476
Product group Antibodies
Overview
- SupplierElabscience
- Product NameNUDT15 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
- UNSPSC12352203