Bio-Connect

NUDT15 Polyclonal Antibody

Research Use Only
RD81724A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetNUDT15
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Reddot Biotech
  • Product Name
    NUDT15 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID55270
  • Target name
    NUDT15
  • Target description
    nudix hydrolase 15
  • Target synonyms
    8-oxo-dGTPase NUDT15; MTH2; mutT homolog 2; nucleoside diphosphate-linked to another moiety X hydrolase 15; nucleotide triphosphate diphosphatase NUDT15; nudix (nucleoside diphosphate linked moiety X)-type motif 15; NUDT15D; probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15; probable 8-oxo-dGTP diphosphatase NUDT15
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203