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NV03

NV03

T12271
TargetMol Chemicals
CAS Number2448341-58-8
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Product group Chemicals
Molecular Weight389.52
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    NV03
  • Delivery Days Customer
    65
  • CAS Number
    2448341-58-8
  • Category Supplier
    Chemical
  • Chemical Name
    NV03
  • Molecular Formula
    C19H27N5O2S
  • Molecular Weight
    389.52
  • Scientific Description
    NV03 is a potent and selective antagonist of UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)- H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a K d of 2.4 uM. NV03 is a possible application as anticancer therapeutics [1].
  • Shelf life instruction
    3 years
  • SMILES
    CC=1N2C(=C(C)C3=C2C=CS3)C(=O)N(CC(NCCCN(CC)CC)=O)N1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Senisterra G, et al. Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain. SLAS Discov. 2018 Oct;23(9):930-940.
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