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ProductsBack/NVP-LDE225 [956697-53-3]

NVP-LDE225 [956697-53-3]

Research Use Only
N859614
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 234,00
5 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    NVP-LDE225 [956697-53-3]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    DMSO:97 mg/mL (199.79 mM); Ethanol:97 mg/mL warmed (199.79 mM); Water insoluble
  • Scientific Description
    Smo inhibitor.; Erismodegib, Sonidegib, LDE225
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Ferguson J, Hannam S, Toholka R, et al. Hair Loss and Hedgehog Inhibitors - A Class Effect? Br J Dermatol. 2014 Dec 18. [Epub ahead of print]. PMID: 25523648. D'Amato C, Rosa R, Marciano R, et al. Inhibition of Hedgehog signalling by NVP-LDE225 (Erismodegib) interferes with growth and invasion of human renal cell carcinoma cells. Br J Cancer. 2014 Sep 9;111(6):1168-79. PMID: 25093491. Nanta R, Kumar D, Meeker D, et al. NVP-LDE-225 (Erismodegib) inhibits epithelial-mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2Rgamma null mice by regulating Bmi-1 and microRNA-128. Oncogenesis. 2013 Apr 8;2:e42. PMID: 23567619.