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ProductsBack/NVP-TAE684 [761439-42-3]

NVP-TAE684 [761439-42-3]

Research Use Only
N8760
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 345,00
10 mg
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More than 130 suppliers
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    NVP-TAE684 [761439-42-3]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    DMSO 3 mg/mL (4.88 mM); Water Insoluble; Ethanol Insoluble
  • Scientific Description
    ALK, c-Fes, LRRK2 inhibitor.; TAE684
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Hellwig S, Miduturu CV, Kanda S, et al. Small-molecule inhibitors of the c-Fes protein-tyrosine kinase. Chem Biol. 2012 Apr 20;19(4):529-40. PMID: 22520759. Zhang J, Deng X, Choi HG, et al. Characterization of TAE684 as a potent LRRK2 kinase inhibitor. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1864-9. PMID: 22335897. Cerchietti L, Damm-Welk C, Vater I, et al. Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas. PLoS One. 2011 Apr 8;6(4):e18436. PMID: 21494621. Galkin AV, Melnick JS, Kim S, et al. Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):270-5. Erratum in: Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):2025. PMID: 17185414.