NVS-PAK1-1

Biorbyt

NVS-PAK1-1 [1783816-74-9]

16

1783816-74-9

Research Use Only

C23H25ClF3N5O

479.93

NVS-PAK1-1 potently inhibits autophosphorylation of PAK1 (S144) at 0.25 microM in the Su86.86 cell line and MEK S289 phosphorylation with an IC50 = 0.21 in Su86.86 cells in which PAK2 is downregulated.

CC(C)NC(=O)N1CC[C@@H](C1)NC2=NC3=C(C=CC(=C3)F)N(C4=C2C=C(C=C4)Cl)CC(F)F

12352200