O6BTG-C8-alphaGlu

MedChem Express

O6BTG-C8-alphaGlu [793035-88-8]

5

Research Use Only

O6BTG-C8-alphaGlu is an O6-methylguanine-DNA methyltransferase ( MGMT ) inhibitor with an IC 50 of 0.45 microM. At a concentration of 0.1 microM, O6BTG-C8-alphaGlu can completely inhibit MGMT in HeLaS3 cells. Even when applied chronically at high doses (up to 20 microM), it does not exhibit cytotoxicity. O6BTG-C8-alphaGlu is suitable for research on MGMT -related cancer diseases [1] .

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