OATD-02 (hydrochloride)

MedChem Express

OATD-02 (hydrochloride)

5

Research Use Only

99.88

C12H26BClN2O4

308.61

OATD-02 hydrochloride is the hydrochloride salt form of OATD-02 (HY-155108). OATD-02 hydrochloride an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 hydrochloride bolishes tumor immunosuppression induced by both arginases. OATD-02 hydrochloride can be used for melanoma study[1].

N[C@]1(C(O)=O)C[C@H](CCB(O)O)CC[C@H]1CN(C)C.[H]Cl

-20°C

12352200