Bio-Connect

OGG1 Polyclonal Antibody

RD81618A
Reddot Biotech
TargetOGG1
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    OGG1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Concentration
    1 mg/ml
  • Gene ID4968
  • Target name
    OGG1
  • Target description
    8-oxoguanine DNA glycosylase
  • Target synonyms
    8-hydroxyguanine DNA glycosylase; AP lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; MUTM; N-glycosylase/DNA lyase; OGG1 type 1f; OGH1
  • Scientific Description
    This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203