OGG1 Polyclonal Antibody
RD81618A
TargetOGG1
Product group Antibodies
Overview
- SupplierReddot Biotech
- Product NameOGG1 Polyclonal Antibody
- Delivery Days Customer5
- Concentration1 mg/ml
- Gene ID4968
- Target nameOGG1
- Target description8-oxoguanine DNA glycosylase
- Target synonyms8-hydroxyguanine DNA glycosylase; AP lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; MUTM; N-glycosylase/DNA lyase; OGG1 type 1f; OGH1
- Scientific DescriptionThis gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
- Storage Instruction-20°C
- UNSPSC12352203