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Olaparib [763113-22-0]

Research Use Only
O4402
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 154,00
10 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Olaparib [763113-22-0]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    DMSO (10 mg/ml), DMF (3 mg/ml)
  • Scientific Description
    PARP1/2 inhibitor.; AZD2281, KU-0059436, Lynparza
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Lee JM, Ledermann JA, Kohn EC. PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies. Ann Oncol. 2013 Nov 12. [Epub ahead of print]. PMID: 24225019. Olaparib Enters Phase III Clinical Testing. Cancer Discov. 2013 Nov;3(11):1210. PMID: 24203936. Postel-Vinay S, Bajrami I, Friboulet L, et al. A high-throughput screen identifies PARP1/2 inhibitors as a potential therapy for ERCC1-deficient non-small cell lung cancer. Oncogene. 2013 Nov 21;32(47):5377-87. PMID: 23934192. Kortmann U, McAlpine JN, Xue H, et al. Tumor growth inhibition by olaparib in BRCA2 germline-mutated patient-derived ovarian cancer tissue xenografts. Clin Cancer Res. 2011 Feb 15;17(4):783-91. PMID: 21097693.