Olaparib [763113-22-0]
O4402
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameOlaparib [763113-22-0]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatDMSO (10 mg/ml), DMF (3 mg/ml)
- Scientific DescriptionPARP1/2 inhibitor.; AZD2281, KU-0059436, Lynparza
- Storage Instruction4°C
- UNSPSC12352200
References
- Lee JM, Ledermann JA, Kohn EC. PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies. Ann Oncol. 2013 Nov 12. [Epub ahead of print]. PMID: 24225019. Olaparib Enters Phase III Clinical Testing. Cancer Discov. 2013 Nov;3(11):1210. PMID: 24203936. Postel-Vinay S, Bajrami I, Friboulet L, et al. A high-throughput screen identifies PARP1/2 inhibitors as a potential therapy for ERCC1-deficient non-small cell lung cancer. Oncogene. 2013 Nov 21;32(47):5377-87. PMID: 23934192. Kortmann U, McAlpine JN, Xue H, et al. Tumor growth inhibition by olaparib in BRCA2 germline-mutated patient-derived ovarian cancer tissue xenografts. Clin Cancer Res. 2011 Feb 15;17(4):783-91. PMID: 21097693.