Oleanolic Acid [508-02-1]

Chen JY, Zhang L, Zhang H, et al. Triggering of p38 MAPK and JNK Signaling is Important for Oleanolic Acid-Induced Apoptosis via the Mitochondrial Death Pathway in Hypertrophic Scar Fibroblasts. Phytother Res. 2014 Apr 6. [Epub ahead of print]. PMID: 24706573. Ghosh S, Bishayee K, Khuda-Bukhsh AR. Oleanolic acid isolated from ethanolic extract of Phytolacca decandra induces apoptosis in A375 skin melanoma cells: drug-DNA interaction and signaling cascade. J Integr Med. 2014 Mar;12(2):102-14.PMID: 24666676. Kim JY, Cheon YH, Oh HM, et al. Oleanolic acid acetate inhibits osteoclast differentiation by downregulating PLCgamma2-Ca(2+)-NFATc1 signaling, and suppresses bone loss in mice. Bone. 2014 Mar;60:104-11. PMID: 24361669. Kim SH, Hong JH, Lee YC. Oleanolic acid suppresses ovalbumin-induced airway inflammation and Th2-mediated allergic asthma by modulating the transcription factors T-bet, GATA-3, RORgammat and Foxp3 in asthmatic mice. Int Immunopharmacol. 2014 Feb;18(2):311-24. PMID: 24374304.