Olsalazine-d3,15N

MedChem Express

Olsalazine-d3,15N

5

Research Use Only

C14H7D3N 15NO6

306.25

Olsalazine-d3,15N is 15N and deuterated labeled Olsalazine (HY-B0174A). Olsalazine is a potent inhibitor of macrophages chemotaxis to LTB4 with an IC50 value of 0.39 mM, also reduces the synthesis of 5-hydroxyeicosatetraenoic acid (5-HETE), 11-HETE, 12-HETE, and 15-HETE in polymorphonuclear leukocyte (PMNL) and mononuclear cells (MNL). Olsalazine can be used for researching ulcerative colitis. Anti-inflammatory activity[1][2].

O=C(O)C1=C(O)C=CC(/N=[15N]/C2=C([2H])C(C(O)=O)=C(O)C([2H])=C2[2H])=C1

12352200