
Western Blot Positive WB detected in: PC-3 whole cell lysate All lanes: OMA1 antibody at 2.7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 61, 56 kDa Observed band size: 56 kDa
OMA1 Antibody
CSB-PA856923LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetOMA1
Overview
- SupplierCusabio
- Product NameOMA1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID115209
- Target nameOMA1
- Target descriptionOMA1 zinc metallopeptidase
- Target synonyms2010001O09Rik; DAB1; metalloendopeptidase OMA1, mitochondrial; metalloprotease-related protein 1; MPRP1; MPRP-1; OMA1 homolog, zinc metallopeptidase; OMA1 zinc metallopeptidase homolog; overlapping activity with M-AAA protease; overlapping with the m-AAA protease 1 homolog; peptidase; YKR087C; zinc metallopeptidase OMA1; ZMPOMA1
- HostRabbit
- IsotypeIgG
- Protein IDQ96E52
- Protein NameMetalloendopeptidase OMA1, mitochondrial
- Scientific DescriptionMetalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203