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OMG Polyclonal Antibody

RD79196A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetOMG
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    OMG Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.4 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4974
  • Target name
    OMG
  • Target description
    oligodendrocyte myelin glycoprotein
  • Target synonyms
    oligodendrocyte-myelin glycoprotein; OMGP
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells; from dorsal root ganglion explants in which growth cone collapse was observed; from rat retinal ganglion neurons; and from NG108 and PC-12 cells.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203