Bio-Connect

OneStep Polymer HRP anti-mouse/rat/rabbit (Ready-to-Use)

GTX83398
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityMouse, Rabbit, Rat
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Overview

  • Supplier
    GeneTex
  • Product Name
    OneStep Polymer HRP anti-mouse/rat/rabbit (Ready-to-Use)
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Conjugate
    HRP
  • Scientific Description
    Immunohistochemistry (IHC) is the localization of antigens in tissue sections/cells using antibodies as specific reagents. Visualization of antibody signal is often significantly improved using the biotin-avidin amplification system. This system, however, adds significant time to experimental protocols and results in higher background due to the presence of endogenous biotin in tissue. Kit Components: polymer 100 ml (The polymer is composed of secondary antibodies (several units)+ HRP (several units)) GeneTexs One-Step anti-mouse/rat/rabbit IgG (H+L) uses the power of next-generation Polymer technology to provide dramatic signal amplification without the need for biotin. This reagent has been shown to provide increased sensitivity and detection, while reducing the incubation time and required quantity of primary antibody. This reagent can be used to enhance staining of membranes, cytoplasmic and nuclear antigens. It provides the user with a rapid and easy to use IHC detection system. Features and Benefits - Lower background: Amplification without biotin avoids background from endogenous biotin - Higher sensitivity than standard IHC detection - Faster: Staining time reduced to 15 minutes! - Compatible with either manual or automated systems - Better results on difficult-to-work antibodies and nuclear staining - Save cost due to further dilution of primary antibody
  • Reactivity
    Mouse, Rabbit, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

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  • Chen YH, Wu JX, Yang SF, et al. Anticancer Effects and Molecular Mechanisms of Apigenin in Cervical Cancer Cells. Cancers (Basel). 2022,14(7). doi: 10.3390/cancers14071824
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  • Chen YH, Wu JX, Yang SF, et al. Metformin Potentiates the Anticancer Effect of Everolimus on Cervical Cancer In Vitro and In Vivo. Cancers (Basel). 2021,13(18). doi: 10.3390/cancers13184612
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  • Chen YH, Chen YC, Lin CC, et al. Synergistic Anticancer Effects of Gemcitabine with Pitavastatin on Pancreatic Cancer Cell Line MIA PaCa-2 in vitro and in vivo. Cancer Manag Res. 2020,12:4645-4665. doi: 10.2147/CMAR.S247876
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  • Kang N, Shen W, Gao H, et al. Antischistosomal Properties of Hederacolchiside A1 Isolated from Pulsatilla chinensis. Molecules. 2018,23(6). doi: 10.3390/molecules23061431
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  • Xu F, Li Z, Zheng X, et al. SIRT1 mediates the effect of GLP-1 receptor agonist exenatide on ameliorating hepatic steatosis. Diabetes. 2014,63(11):3637-46. doi: 10.2337/db14-0263
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