Onjisaponin B
HY-N2099
Overview
- SupplierMedChem Express
- Product NameOnjisaponin B [35906-36-6]
- Delivery Days Customer10
- CAS Number35906-36-6
- CertificationResearch Use Only
- Estimated Purity99.10
- Molecular FormulaC75H112O35
- Molecular Weight1573.67
- Scientific DescriptionOnjisaponin B is an orally active natural product derived from Polygala tenuifolia. Onjisaponin B inhibits NF-kappaB p65. Onjisaponin B enhances autophagy and accelerates the degradation of mutant alpha-synuclein and huntingtin. Onjisaponin B reduces beta-amyloid (Abeta) production. Onjisaponin B reduces radiation-induced cell apoptosis. Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB[1][2][3][4].
- SMILESOC[C@](C1=CC[C@]2([H])[C@]3(C[C@H](O)[C@@H]4O[C@]([C@@H]([C@@H](O)[C@@H]5O)O)([H])O[C@@H]5CO)C)(CC[C@]6(C(O[C@H](O[C@H](C)[C@H](OC(/C=C/C7=CC=C(OC)C=C7)=O)[C@@H]8O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)[C@@H]8O[C@@](O[C@@H](C)[C@H](O[C@@](OC[C@@H](O[C@]([C@@H]([C@@H](O)[C@H]%10O)O)([H])O[C@@H]%10CO)[C@@H]%11O)([H])[C@@H]%11O)[C@H]%12O)([H])[C@@H]%12O)=O)[C@@]1([H])CC(C)(C)CC6)[C@@]2(CC[C@@]3([H])[C@]4(C)C(O)=O)C
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200