Ontorpacept

MedChem Express

Ontorpacept

10

Research Use Only

99.57

Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPalpha N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity[1].

-80°C

12352203