Onvansertib (NMS-P937)

Selleck Chemicals

Onvansertib (NMS-P937) [1034616-18-6]

9

Research Use Only

...

Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosis in cancer cell lines and inhibits tumor growth. Phase 1.

-80°C

51202000