Bio-Connect

OPRK1 Polyclonal Antibody

RD81686A
Reddot Biotech
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetOPRK1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    OPRK1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4986
  • Target name
    OPRK1
  • Target description
    opioid receptor kappa 1
  • Target synonyms
    kappa opioid receptor; kappa-type opioid receptor; KOP; KOR; KOR1; K-OR-1; KOR-1; Opiate receptor, kappa-1; OPRK
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203