ORC2 Polyclonal Antibody
RD266540A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetORC2
Overview
- SupplierReddot Biotech
- Product NameORC2 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4999
- Target nameORC2
- Target descriptionorigin recognition complex subunit 2
- Target synonymsORC2L; origin recognition complex protein 2 homolog; origin recognition complex subunit 2; origin recognition complex, subunit 2 homolog
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203