Oroxin A [57396-78-8]

MedChem Express

Oroxin A [57396-78-8]

9

57396-78-8

Research Use Only

99.76

C21H20O10

432.38

Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARgamma agonist that can activate PPARgamma transcriptional activation. Oroxin A activates PPARgamma by docking into the PPARgamma protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against alpha-glucosidase and an antioxidant capacity[1]. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence[2].

O=C1C=C(C2=CC=CC=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C(O)C(O)=C13

-20°C,2°C to 8°C

12352200