Oseltamivir Phosphate [204255-11-8]
O7218
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameOseltamivir Phosphate [204255-11-8]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- Scientific DescriptionViral neuraminidase inhibitor, potential MAO-A inhibitor.
- Storage Instruction4°C
- UNSPSC12352200
References
- Huang L, Cao Y, Zhou J, et al. A conformational restriction in influenza A virus neuraminidase binding site by R152 caused the combinational effect of I222T with H274Y on oseltamivir resistance. Antimicrob Agents Chemother. 2013 Dec 23. [Epub ahead of print]. PMID: 24366752. Vavricka CJ, Liu Y, Kiyota H, et al. Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors. Nat Commun. 2013;4:1491. PMID: 23422659. Hiasa M, Isoda Y, Kishimoto Y, et al. Inhibition of MAO-A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti-influenza agent oseltamivir. Br J Pharmacol. 2013 May;169(1):115-29. PMID: 23320399. Jefferson T, Jones MA, Doshi P, et al. Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Cochrane Database Syst Rev. 2012 Jan 18;1:CD008965. PMID: 22258996.