Oseltamivir . phosphate salt [204255-11-8]
AG-CR1-3714
Overview
- SupplierAdipoGen Life Sciences
- Product NameOseltamivir . phosphate salt [204255-11-8]
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity>98%
- Hazard InformationNon-hazardous,Warning
- Molecular FormulaC16H28N2O4 . H3PO4
- Molecular Weight312.4 . 98.0
- Scientific DescriptionChemical. CAS: 204255-11-8. Formula: C16H28N2O4 . H3PO4. MW: 312.4 . 98.0. Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. It is an antiviral prodrug targeted against the influenza viruses. Once hydrolyzed in the liver to its active metabolite, oseltamivir carboxylate, it can competitively inhibit viral neuraminidase (IC50s=0.1-4.9nM for influenza neuraminidases A and B). The enzyme cleaves the sialic acid which is found on glycoproteins on the surface of human cells that helps new virions to exit the cell. Thus oseltamivir is blocking the release of new viral particles from a host cell. Oseltamivir phosphate is used clinically to treat influenza A and influenza B, and to prevent flu after exposure. It potentially could be used to reduce the spread of the SARS-CoV2 and counteract against the transmission of COVID-19. - Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. It is an antiviral prodrug targeted against the influenza viruses. Once hydrolyzed in the liver to its active metabolite, oseltamivir carboxylate, it can competitively inhibit viral neuraminidase (IC50s=0.1-4.9nM for influenza neuraminidases A and B). The enzyme cleaves the sialic acid which is found on glycoproteins on the surface of human cells that helps new virions to exit the cell. Thus oseltamivir is blocking the release of new viral particles from a host cell. Oseltamivir phosphate is used clinically to treat influenza A and influenza B and to prevent flu after exposure. It potentially could be used to reduce the spread of the SARS-CoV-2 and counteract against the transmission of COVID-19.
- SMILESO=P(OO)=O.N[C@@H]1[C@@H](NC(C)=O)[C@H](OC(CC)CC)C=C(C(OCC)=O)C1.[HH]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352200