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ProductsBack/OSI-027 [936890-98-1]

OSI-027 [936890-98-1]

Research Use Only
O7332
LKT Laboratories
Estimated Purity≥99%
Product group Chemicals
€ 407,00
10 mg
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More than 130 suppliers
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    OSI-027 [936890-98-1]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥99%
  • Format
    DMSO 18 mg/mL (44.28 mM); Water Insoluble; Ethanol Insoluble
  • Scientific Description
    mTOR inhibitor.
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Li H, Lin J, Wang X, et al. Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer. Breast Cancer Res Treat. 2012 Aug;134(3):1057-66. PMID: 22476852. Gupta M, Hendrickson AE, Yun SS, et al. Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies. Blood. 2012 Jan 12;119(2):476-87. PMID: 22080480. Falcon BL, Barr S, Gokhale PC, et al. Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors. Cancer Res. 2011 Mar 1;71(5):1573-83. PMID: 21363918. Vakana E, Sassano A, Platanias LC. Induction of autophagy by dual mTORC1-mTORC2 inhibition in BCR-ABL-expressing leukemic cells. Autophagy. 2010 Oct;6(7):966-7. PMID: 20699667.