Osunprotafib [2489404-97-7]

TargetMol Chemicals

Osunprotafib [2489404-97-7]

9

Chemical

Research Use Only

Osunprotafib

98.24%

C17H24FN3O4S

385.45

Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. [1] Osunprotafib (ABBV-CLS-484) stimulates the tumor microenvironment and promotes natural killer cell and CD8 T cell function and enhances T cell anti-tumor immunity by enhancing JAK-STAT signaling and reducing T cell dysfunction. [2]

3 years

CC(C)CCN[C@@H]1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2C1

-20°C

12352200