OTUB1/USP8-IN-1 (TFA)

MedChem Express

OTUB1/USP8-IN-1 (TFA)

5

Research Use Only

99.56

C24H17ClF4N2O6

540.85

OTUB1/USP8-IN-1 TFA is the TFA salt form of OTUB1/USP8-IN-1 (HY-151563). OTUB1/USP8-IN-1 TFA is a dual inhibitor for OTUB1/USP8, IC50 for OTUB1 and USP8 is 0.17 and 0.28 nM, respectively. OTUB1/USP8-IN-1 TFA inhibits proliferation of NSCLC cells. OTUB1/USP8-IN-1 TFA exhibits good pharmacokinetic characters in ICR mouse, and exhibits antitumor activity in H1975 xenograft mouse model[1].

O=C(C1=C2OC(C3=C(F)C=CC(O[C@H]4CN(C)CC4)=C3Cl)=N1)C5=C(C=CC=C5)C2=O.OC(C(F)(F)F)=O

2°C to 8°C

12131703