OTX2 Polyclonal Antibody
RD81687A
TargetOTX2
Product group Antibodies
Overview
- SupplierReddot Biotech
- Product NameOTX2 Polyclonal Antibody
- Delivery Days Customer5
- Concentration1 mg/ml
- Gene ID5015
- Target nameOTX2
- Target descriptionorthodenticle homeobox 2
- Target synonymsCPHD6; homeobox protein OTX2; MCOPS5; orthodenticle homolog 2
- Scientific DescriptionThis gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.
- Storage Instruction-20°C
- UNSPSC12352203